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      • PROOF Centre Collaboration Focuses on Prognostic Biomarkers for Chronic Kidney Disease
      • PROOF Centre to Begin Clinical Validation of Heart Transplant Rejection Liquid Biopsy Test Using the HTG EdgeSeq System, a Next-Generation Sequencing (NGS)-Based Platform
      • Mapping BC’s Path to Personalized Medicine
      • PROOF Centre & IO Informatics to Present at Partnering for Cures Conference
      • Centres of Excellence Align to Advance Novel Therapeutics and Diagnostics
      • PROOF Centre and MRM Proteomics Collaborate with the Jain Foundation to Identify Blood-Based Biomarkers of LGMD2B/Miyoshi Muscular Dystrophy
      • The PROOF Centre of Excellence Partners with HTG Molecular Diagnostics to Begin Clinical Validation of Heart Transplant Rejection Blood Test
      • PROOF Centre of Excellence and MRM Proteomics Partner to Bring New Tests to Clinic
      • New Blood Tests to put Clinical Trials for Allergic Asthma on the Fast Track
      • New Web-based App to Help Clinicians Improve Patient Care
      • The PROOF Centre of Excellence Partners with OriGene Technologies on Heart & Kidney Transplant Biomarker Program
      • Time to breathe a sigh of relief
      • PROOF Centre and Adiga Life Sciences launch biomarker discovery collaboration
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  • Abhinav Checkervarty, PhD Student
  • Dr. Amrit Singh, Postdoctoral Fellow
  • Dr. Ji-Young Kim, Assay Development Scientist
  • Estefania Espin, PhD Student
  • Kang Dong, PhD Student
  • Lucy Hao, Co-op Student
  • Shanay Nishua
  • Simran Samra, Graduate Student
  • Daniel He, Graduate Student
  • Dr. Chengliang Yang, MD, Research Associate
  • Mr. Casey Shannon, Director of Data Science
  • Ms. Paula Piper, Administrator & Communications Coordinator
  • Dr. Robert Balshaw, Special Advisor – Statistical Lead
  • Board of Directors
  • Management Team
  • Operations Team
  • Mr. Frank Holler, Chairman of the Board
  • Dr. Suzanne Vercauteren
  • Dr. Bruce McManus
  • Dr. Darryl Knight
  • Dr. Donald Brooks
  • Mr. Bruce Milley
  • Mr. Richard Rees
  • Dr. Raymond Ng, Chief Informatics Officer
  • Dr. Scott Tebbutt, CEO & Chief Scientific Officer
  • Dr. Karen Lam, Chief Business Officer
  • Dr. Zsuzsanna Hollander, Chief Data Officer
  • Ms. Sara Assadian, Director, Clinical Research
PROOF Centre

Media Coverage

  • Genome BC announces $1M in funding to support four unique projects, including that of PROOF, aimed at enabling discoveries to address unmet clinical healthcare needs, Newswire, April 12, 2023.
  • Revolutionizing the recovery journey: How translational research is improving the lives of heart transplant patients, UBC Faculty of Medicine, February 8, 2021
  • Peripheral blood analysis shows benefit of peptide immunotherapy for cat allergy, AllerGen Inc, January 8, 2021
  • Researchers unlock TB vaccine puzzle in findings that could save millions of newborns, UBC Faculty of Medicine, May 6, 2020.
  • Antiviral drug used to treat Hep C may help COVID-19 patients, new study finds, The Daily Scan, April 28, 2020
  • Newborns study to guide development of better infant vaccines: UBC, CTV News Vancouver, March 2019
  • IO Informatics releases the inaugural issue of LINKED, IO Informatics, May 2016
  • Metabolomics in Precision Medicine, GEN Genetic Engineering & Biotechnology News, May 2015
  • Searching for PROOF of person-specific prevention and care, Biotechnology Focus, March 2015
  • Meet & Greet with Dr. Bruce McManus, PHC News, March 5, 2015
  • Using genomics to uncover deadly lung disease, Promise, Spring/Summer 2014.
  • New treatment for chronic obstructive pulmonary disease, Global BC, December 11, 2013.
  • COPD patients starting to breathe easier, Biotechnology Focus, December 6, 2013.
  • University of British Columbia Team Lands C$7.2M to Develop COPD Dx, GenomeWeb, December 5, 2013.
  • BC Centres of Excellence align to advance novel therapeutics and diagnostics, Biotechnology Focus, November 29, 2013.
  • Transplant: How research is improving lives now, Global BC, November 21, 2013.
  • Jain Foundation Steps Up Efforts To Find Cure For Muscular Dystrophy, Genetic Engineering & Biotechnology News, October 16, 2013.
  • PROOF, MRM Proteomics Collaborating with Jain Foundation on Muscular Dystrophy Markers, GenomeWeb, October 16, 2013.
  • HTG Validating PROOF Centre’s Heart Transplant Rejection Assay, GenomeWeb, September 25, 2013
  • Bruker and the Genome British Columbia Proteomics Centre at the University of Victoria Announce Collaboration on Development of High Throughput iMALDI Assays, BiomedReports, April 18, 2013.
  • Biomarker signatures and healthcare solutions, Biotechnology Focus, February 11, 2013.
  • PROOF for FFPE samples, Drug Discovery News, January 11, 2013.
  • IO Informatics Moves into Personalized Medicine with Launch of Healthcare Arm, BioInform at GenomeWeb, December 7, 2012.
  • Making excellent care for acute heart failure patients a priority through innovation and research, Hospital News, December 3, 2012.
  • HTG to Commercialize PROOF’s COPD Risk Stratification Test; Aims for Launch Next Year, Pharmacogenomics Reporter at GenomeWeb, December 5, 2012.
  • Signals Intelligence, UBC Medicine Magazine, Fall 2012.
  • News Hour – Smaller charities fight for support, Global TV BC, December 5, 2012.
  • Blood tests could replace biopsies by 2016, The Province, November 22, 2012.
  • Opinion: B.C. can be leader in ensuring biotech advances help improve health care delivery, Vancouver Sun, September 17, 2012.
  • IO Informatics Partners with PROOF to Develop Risk Assessment Software for Clinical Use, BioInform at GenomeWeb, September 14, 2012.
  • PROOF, IO Informatics to Develop App Aimed at Heart, Lung, and Kidney Disease, GenomeWeb Daily News, September 11, 2012.
  • Origene Collaborating with PROOF Centre on Protein Diagnostics for Heart and Kidney Transplants, GenomeWeb Daily News, July 27, 2012.
  • Networks and Centres in the News, ExcelleNCE Newsletter, July 2012.
  • A simple test to predict lung attacks is on the horizon, Hospital News, July 6, 2012.
  • Especially for you: Personalized medicine pinpoints best treatment given a patient’s genetic makeup, LifeSciences BC Annual Magazine, 2012.
  • Time to breathe a sigh of relief: A simple test to predict lung attacks is on the horizon, D’Vine Providence, May/ June 2012.
  • 2012 Milton Wong Award for Leadership – Bruce McManus, LifeSciences BC, April 26, 2012.
  • Canada’s PROOF Centre to Develop Risk Stratification Test to Personalize COPD Treatment, Pharmacogenomics Reporter at GenomeWeb, April 25, 2012.
  • PROOF Centre uses GenomeBC funds for COPD Dx, GenomeWeb Daily News, April 17, 2012.
  • Precision medicine is semantic medicine. semanticweb.com, April 18, 2012.
  • PROOF, Adiga collaborate on biomarkers for allergy vaccine. GenomeWeb Daily News, April 6, 2012.
  • A pounding heart and warm feet are signs of new life for this heart patient. D’Vine Providence, Spring 2012.
  • Clinical implementation of diagnostic biomarker assays in heart and kidney transplantation, Part I and Part II. Genome BC 2012 Winter Symposium, January 24, 2012.
  • Predicting problems. Macleans.ca, November 17, 2011.
  • Glimpsing into a brighter future: The fourth annual heart transplant patient education day. D’Vine Providence, November 2011.
  • Breath of Life: Biomarker research could improve detection and treatment of deadly lung disease. Promise, Fall/ Winter 2011.
  • A marked improvement on diagnosis. National Post, September 29, 2011.
  • Biomarkers to diagnose and prevent ‘lung attacks’ that can kill. Hospital News, July 2011.
  • The future of healthcare. Vancouver Sun, June 20, 2011.
  • Research Profiles – Medicines get personal: the promise of biomarkers. Canadian Institutes of Health Research, May 4, 2011.
  • Research Profiles –  Blood tests versus biopsies: The biomarker breakthrough. Canadian Institutes of Health Research, May 4, 2011.
  • A single drop of blood could detect the risk of serious disease. Networks of Centres of Excellence of Canada, May 2011.
  • Heart transplant recipient has faith in biomarker research. Hospital News, May 2011.
  • Session to present strategies for long-term survival. American Transplant Congress (ATC) Daily, May 2, 2011.
  • Case study: Applied semantic knowledgebase for detection of patients at risk of organ failure through immune rejection. The World Wide Web Consortium (W3C), March 2011.
  • St. Paul’s hospital leads in HIV-AIDS treatment and research. The Georgia Straight, March 29, 2011.
  • DNA mismatch reveals organ rejection. Nature News, March 28, 2011.
  • New UVic spectrometer can detect cardiovascular disease with single blood test. Time Colonist, January 24, 2011.

About the PROOF Centre

The PROOF (Prevention of Organ Failure) Centre of Excellence is a not-for-profit organization that develops blood tests to better predict, diagnose, manage and treat disease, by harnessing the power of clinical, molecular and computational science.

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