The PROOF (Prevention of Organ Failure) Centre develops blood tests to better predict, diagnose, manage and treat heart, lung and kidney disease, by harnessing the power of clinical, molecular and computational science.
Our Team

Our Team

By uniting a cross-disciplinary hub of people and teams in a collaborative, not-for-profit model, the PROOF Centre can speed up development of new blood tests to address organ failure and disease.

Our Programs

Our Programs

The PROOF Centre has biomarker programs to develop simple blood tests for transplant patients and patients with chronic organ disease. Current programs focus on heart failure, COPD, and chronic kidney disease.

Our Services

Our Services

The PROOF Centre’s service arm provides expertise in computation, “-omic” science and biomarker workflow to organizations seeking to discover, develop and implement blood-based molecular biomarkers in a clinical setting.

Publications

2014 Singh A, Yamamoto M, Ruan J, Choi JY, Gauvreau GM, Olek S, Hoffmueller U, Carlsten C, FitzGerald MJ, Boulet L-P, O’Byrne PM, Tebbutt SJ. Th17/Treg ratio derived using DNA methylation analysis is associated with the late phase asthmatic response....

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